Sleep-wake rhythm disturbances and perceived sleep in adolescent chronic fatigue syndrome Study by among others professor Wyller. He is a controversial researcher as he doesn't use strict criteria on his patients and as he has a biopsycosocial approach to ME. He has a trial on music therapy as treatment for ME and applied for funds for a trial on Lightning Process (sic) as another treatment. Still, this study could be of interest nevertheless. The study included 120 adolescent CFS-patients and 39 healthy individuals. - The activity measures showed that the CFS patients stayed significantly longer in bed, had a significantly delayed mid-sleep time and a more varied sleep-wake rhythm during weekdays compared with healthy individuals. On the KSQ, the CFS patients reported significantly more insomnia symptoms, sleepiness, awakening problems and a longer sleep onset latency than healthy individuals. These results might indicate that disrupted sleep-wake phase could contribute to adolescent CFS; however, further investigations are warranted.