http://www.huffingtonpost.com/2013/02/26/sleep-deprivation-genes_n_2766341.html?ref=topbar http://www.pnas.org/content/early/2013/02/20/1217154110 This is an interesting article. I was very busy at one time in my life and got very little sleep. Perhaps this changed my immune system to something dysfunctional. (Please delete if there is a problem with posting a link to this article. I was not sure).