Have ongoing sinusitis , responds well to abx but returns when i stop. I have used the beg spray before which contains bactroban, gentamycin and edta to help dissolve biofilms, it worked well but its not cheap and its a pain dealing with compounding pharmacies etc than add shipping cost . In the past i have used bactroban ointment which one places in the side of the nostril and then squeeze your nose etc. It never did much. Recently I thought of just using a bactroban I had on hand and making a spray from the old beg spray bottle i had. Several formulas or recipes online on how to make them. Its very simple. I just used the 40ml spray bottle and warmed up the bactroban ointment and the saline i had in a glass of warm tap water to make it easier to mix. I put the bactroban in first and had a thin implement to help get it all in the bottle , than squirted the saline into the bottle, gave it a stir and a good shake . Too easy. I keep it in the fridge. Started with 2 sprays up each nostril 3 times day then later just twice a day. Keep using it until i finish the bottle , 2 weeks?? I was also using oral abx. The combination seems to work well . The bactroban spray works just as well as the beg spray but alot cheaper. Probably easy to ad edta to the spray from capsules of edta also. Not sure if I will ever get rid of sinus infections but atleast this works and is cost effective .