Ive been on the full Simplified Methylation Protocol for two weeks now. I havent counted the week leading upto taking the full amount of the suppliments. Two days in and i started to feel quite energetic and actually woke up looking forward to taking the protocol. However, for about 3 days now ive been getting the detox symptoms Rick mentioned. Ive got a little cough, the night sweats are back, i get the odd headache, and my body is more fatigued. I did decrease the Hydroxy and B12 drops down to one drop each, i'll work them back up, as my breathing seemed to get 'harder', and when i decreased those, it helped a little. Can anyone tell me if there is an average period for the detox symptoms. I first fell ill last summer 2010, and had a 7 month partial recovery period before falling very ill again this june, i mention that because i watched a video of Ricks talk and he did say that the longer you've been poorly, the worse those detox symptoms can be, but, unless i missed something, he didnt mention how long the detox feelings would last. I DO remember him saying that if you get these flu / original ME symptoms worse on the protocol, to take it as a good sign.