Hi Aquariusgirl, What are the symptoms that you are calling "detox"? The reason I ask is that the term has been applied to a lot of things are actually something else which can be corrected easily and also that can be dangerous. For instance hypokalemia induced by methylation starting up and cell formation proceeding has a whole lot of symptoms that are often called "detox". Hypokalemia, if continued and worsened can cause death. Relief can be had in one hour and future such reaction prevented. If a person is taking NAC or glutathione or glutathione precursors they often have a reaction that is called "NAC detox" or "glutathione detox" which actually is an induced folate and b12 deficiency regardless of what else you are taking. If a person is taking folic acid and/or folinic acid one reaction many people have is a paradoxical folate deficiency that also proceeds into b12 deficiencies if continued long enough. So, to work through this, and find answers for you if possible, and to relieve the symptoms you are experiencing if possible, to start with are you taking folic acid, folinic acid, NAC, glutathione in any way or form or precursor set or undenatured whey? Sometimes the folic acid, NAC or glutathione precursor sets are taken as part of one or more multi-ingredient supplements intentionally or accidentally.