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Significant Improvement Story -- Focus on Thiamine Deficiency

Discussion in 'General Treatment' started by Wayne, Jul 3, 2013.

  1. Little Bluestem

    Little Bluestem Senescent on the Illinois prairie, USA

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    rebar, what form of B1 are you taking?
     
  2. rebar

    rebar

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    as thiamine. Solgar 500 mg.
     
    Little Bluestem likes this.
  3. Snowdrop

    Snowdrop Senior Member

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    Hi all,

    Is anyone who was trying the B1 here still on the protocol?

    If so what type of B1, how much and how is it working?

    Grateful for any info/insights into this.
    SD
     
  4. Little Bluestem

    Little Bluestem Senescent on the Illinois prairie, USA

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  5. rebar

    rebar

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    I recently stopped.
    It did wonders for me initially, I crashed after a couple of months and after that couldn't seem to adjust my dose.
    Some of the benefits have persisted, calmness upon awakening, less of the wired and tired feeling.
    If I start to experience either of the above I'll start it again.
     
    Wayne likes this.
  6. Snowdrop

    Snowdrop Senior Member

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    I'm making some choices as to where to spend limited resources for supplements so feedback from others experience is helpful.
    Thanks for your response rebar.
     
  7. Lynn

    Lynn Senior Member

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    Wayne likes this.
  8. Little Bluestem

    Little Bluestem Senescent on the Illinois prairie, USA

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    Sometimes when something works for a while then stops, it is because you have become depleted in another nutrient that functions together with the first. IF that is your situation and IF you can find out what else you need, then the thiamine might 'work' again.
     
    helen1, MeSci, place and 1 other person like this.
  9. Dannylingo

    Dannylingo

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    You are correct! I noticed a pattern with b vitamins. B2 helped me to one point until I added biotin, then biotin helped more when I added magnesium then manganese. Now I am going to try thiamine since I benifited at the first dose. All you guys should note that b1 works together with niacin, biotin, b2 and manganese. Just look at the kreb cycle chart on this link http://www.health-science-spirit.com/HF5-2.html
     
  10. Lynn

    Lynn Senior Member

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    @Dannylingo
    Thanks for that. I had an extraordinary 6 month run on B1 with more energy than I have had in years.Unfortunately the positive effect has begun to decline for me. I had the worst day yesterday that I have had in months.

    I am taking 1500 mg of B-1. Do you have any suggestions on dosage of the niacin, biotin, b2 and manganese? Are there tests that you can take to check your vitamin balance?

    Thanks for your help.

    Lynn
     
    Wayne likes this.
  11. Dannylingo

    Dannylingo

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    I'm not familiar with tests but what I do kno is that thiamine works with basically all the b vitamins work together and vice versa. I find it odd that no were on this forum does people ever consider the Krebs cycle the core of all there ailments.

    I personally believe methylation issues is secondary to b1,2,3,5,7 deficiencies. Notice how methyl supplements almost always stimulate you, but don't provide you with atp ? Then you crash.

    On the other hand the other b vitamins don't really have a stimulating affect, it's not to say it cant deplete a synergistic vitamin though. For example, if you crash on b1, it coul be anything from niacin to b5 wich work with b1 to form acetyl coa.

    If you have too much acetyl coa and not enough oxaloacetate your acetyl coa will go to waste causing less energy. Next what you need to consider is that you is that you might need to pair up b1 with magnesium since they also pair up to activate a different enzyme in an earlier step. If you want to increase oxaloacetate you need to pair up biotin with manganese and nicotinamide.

    That will increase ox entering the Krebs cycle to join acetyl coa to produce citric acid wich will give you that energy you need from food. I always wondered why people on this forum never consider studying a little bit of text book biochem to understand what they might be lacking after a vitamin stops working. Usually most of you guys just say "it stopped working" and that the end.
     
    Last edited by a moderator: Mar 12, 2014
    Tunguska likes this.
  12. Little Bluestem

    Little Bluestem Senescent on the Illinois prairie, USA

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    {Waving hand wildly} I do! I do! I think I even said so somewhere here, but I don't know where. :ill: :sluggish:
     
    Wayne likes this.
  13. Starfive

    Starfive

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  14. Starfive

    Starfive

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    :nervous:oooops, just meant to comment on reading a biochem textbook, hmmmmm
    I can read a little but can not remember much at all. Also have tons of yellow pads with years of notes of science and supplements that I lack the time to review because I am sleeping so much. Now I don't even know where they are. The ole IQ has been somewhat decimated... no reliable processor.
     
    Wayne likes this.
  15. Wayne

    Wayne Senior Member

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    I start out just about every day thinking this is going to be the day I'm going to go through and make some headway on my own piles of yellow post it and other notebook notes. Almost never happens. Sigh... :(
     
    Last edited: Mar 14, 2014
  16. brenda

    brenda Senior Member

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    Since finding out l am on the autistic spectrum, and that thiamine has proven helpful for autistic kids, l am keen to give it a try after reading this thread. Is anyone still taking it and has anyone found out why they crashed? Also l see that Co-enzymated Source Naturals contains magnesium stearate which l won't take but can't find an alternative. Has anyone a suggestion please? Thanks for your posts on here Wayne.
     
  17. BadBadBear

    BadBadBear Senior Member

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    Interesting thread (albeit a bit dated) - anyone know if supplementing thiamine can improve albumin levels? My serum albumin is always below optimal & does not seem to improve with diet.
     
  18. howirecovered

    howirecovered Senior Member

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    One possibility to consider is that you may have created a folate deficiency which could bring down your methylation system. This is pretty theoretical but I believe the reverse might have happened to me where I created a B-1 deficiency by taking folate.

    TheSLC19A1gene encodes a transporter involved in folate and thiamine uptake and may play a role in intracellular folate distribution. I happen to have flaws on that gene which might have something to do with my CFS and toxicity problems.

    I'm trying to sort all this out now and in the process of ramping up B-1. will probably post about it on my blog later after I have a little more data.
     
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  19. howirecovered

    howirecovered Senior Member

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