Prednisone may eventually be part of the treatment for XMVR I recall both Mikovits and Peterson saying in interviews about XMVR that since it replicates very slowly it is therefore not a good candidate for some of the HIV drugs that target parts of the retrovirus replication cycle... but that cortisone could possibly be used to stimulate XMVR replication and make it susceptible to these drugs. Mikovits also used this feature of the virus to say how well it matches the symptom pattern we seen in CFS/ME: stress often is a trigger for worsening condition. Of course, there is also evidence that cortisol levels not only suppress immune function, but stimulate replication through other mechanisms of various bacteria such as Chlamydia pneumoniae. I'm pretty sure this is true of some other bacteria as well. Some of the speculation in this thread that the common finding in CFS/ME/Fibro of low cortisol levels as a protective response by the body to a cortisol stimulated virus like XMVR could be similar with other invading organisms, and we all know how multiple occult infections are common in our population. As to the "what is a monkey wrench?" question earlier: monkeys, although small, are very strong, and can yank your arm producing an injury commonly referred to as a monkey wrench. This was obviously a metaphor by the poster (or is it an analogy, I get these confused) to the small size but powerful effect of a virus like XMVR.