Hi Peeps I'm a long-term MEer, and was doing a lot better on thyroid meds and following Rich's protocol. Then I had a very stressed bit caring for my brother when he was undergoing chemo (and living in a moldy flat). I am pretty ill now, and have also noticed a sudden decline in my sight. This led to a recent diagnosis of macular degeneration. I'm back to be hot and cold, night sweats, exhausted, confused. I also have long-term issues with a genetic kidney disorder, protozoan infection etc. My ME doc, who I like very much, and respect, has suggested the current manifestation may be partly an allergic/autoimmune response to the bugs I haven't managed to eradicate. She has suggested four months of augmentin, a month of anti-fungals and three weeks of steroids, starting off with a high dose and tapering down. She is very keen on the gut as a means of restoring health, and I don't think she'd suggest this without considering it necessary. On the other hand, having done my parents meds when they were dying of cancer, I am afraid of steroids, and afraid of their effect on underlying infections. Or is it worth the risk to shut off the inflammatory process? Would very much appreciate people's thoughts and experience.