I'm so conflicted about LDN! I've been on this stuff for 5 months and am still out of commission. I started it because of a bad CFS relapse but I also have Hashimoto's and now suspect that a Hashi's flare may have triggered the CFS relapse. LDN has improved pain, cognitive function, and sleep, but it has caused me to develop eczema for the first time ever. LDN has NOT helped the fatigue at all and even made it worse. Cutting back from 4.0 to 1.0 helped some but not completely. But then, I felt awful when I started. I'm wondering if I should try quitting the LDN. Has anyone received the benefits ofusing LDN short term and then been able to quit it without losing the benefits? Thanks!