Thanks again ahmo - I appreciate your input. I'm waiting for the supplements to arrive but in the meantime I have 10 x 1ml hydroxo injections. I'm going to use them to get back to where I was after the loading doses and see what happens if I switch over to the supps. I've been taking methyl sublinguals for weeks now and am seeing no effect whatsoever. Maybe the addition of the adnesylcobalamin or whatever it's called will make a difference but if not I may just stick with the hydroxo injections because I saw such a change with them.