Hello, just plugged my 23andme results in and the only mutations I have are 677ct and shmt1 (+/+). I've never really felt like I have any kind of Cfs or other illness so that's not really what brought me here. Looking more for preventative steps to keep things running smoothly, but there is hardly anything solid on shmt1 (+/+). I have read that it enhances the effect of 677ct though? Thanks for any help.