Strange symptom that flares up periodically, intense itching-burning pain in the area of the lower calf, on BOTH legs, with NO outbreak at all on the skin. I know that shingles can present without rash, but can it also present bilaterally? It's more on the outer side of the lower calves, from around the ankle to about 6 inches up. The skin is so hypersensitive that even light touch is excruciating. Gets very bad at night preventing sleep, and the only thing that has helped so far is to knock myself out with an antihistamine so I can sleep it off. And it's a bit better the next morning, and almost gone during the day. I plan to try some Emuaid cream (tea tree oil, colloidal silver, lysine). My internist doesn't have a clue except that it could be something neurological, but he wanted me to see a dermatologist first to rule out that area, but in my condition I don't want to waste energy on that. I really think it's virally related, whether shingles or some other chronic virus flaring up and attacking the nerves in that area. Does this sound consistent at all with any of the chronic viruses associated with CFS/ME? I'm sure I have plenty of them, although haven't been tested in recent years.