https://www.sciencedaily.com/releases/2016/07/160713100855.htm
Shedding new light on protein aggregates and the diseases they cause
Date:
July 13, 2016
Source:
Genetics Society of America
Summary:
Researchers have developed a system capable of quickly screening millions of yeast cells to measure protein aggregates. Proteins regulate all of the processes that keep cells alive, but when misfolded they can clump into large aggregations, a phenomenon associated with diseases including Alzheimer's, Huntington's and Parkinson's."
Though seen in many types of cells, their causes and effects are not well understood. In addition to a number of serious neurodegenerative diseases, aggregates are associated with prion diseases, a class of disorders in which malfunctioning proteins act as infectious agents. At the same time, some protein aggregations have been associated with beneficial functions, such as facilitating the formation of memories and protecting cells from viruses.