Hello, I have had M.E. for about 10 years but only developed ocd within the past 3 years. I became bedridden in 09 which went on for about a year, and in that time had constant adrenaline and tachycardia which was eventually diagnosed with hyperadregenic POTS. A couple years later I woke up one day with horrible ocd; I can't control or combat the thoughts at all and now I can't rest, relax, or sleep because of them so I've been declining rapidly. I see a very respected psychiatrist and we've tried all the FDA approved drugs, we have also tried anti-psychotics, tri-cyclics, and I am currently taking klonopin and xanax so I am drugged all the time. I have been doing CBT with a great psychologist for 4 years now. None of this has helped at all, none. I THINK the CFS is causing it b/c nothing else it helping. But that is a general statement obviously..................... My question is: what could be causing this ocd (physiologically speaking)? Has anybody dealt with it to this severity and what helped? Any suggestions are welcome, thank-you for your time, I just merely want to be free of this torture.