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Seeing an Immunlogist on Friday...what tests?

Discussion in 'Diagnostic Guidelines and Laboratory Testing' started by Scavo86, Jul 25, 2012.

  1. Scavo86

    Scavo86 Senior Member

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    England
    Hi All

    Am seeing an Immunologist on Friday in London, I have a few ideas as to what battery of tests I should have as an initial ME/CFS profile (see below), but can anybody think of any additional ones to ask/plead for? Bearing in mind this is the UK, so we may not be able to go too exotic with the bloods, thanks ever so much :)

    Natural Killer Cell Function Assay
    HHV6 IgG & IgM
    EBV VCA IgG & IgM
    EBV EA (r+d) IgG
    EBNA Ab IgG
    HSV 1/2 IgG & IgM
    CMV IgG & IgM
    Parvovirus B19 IgG & IgM
    VZV IgG & IgM
    Mycoplasma pneumoniae IgG & IgM
    Chlamydia pneumoniae IgG & IgM
    Lymphocyte Subset Panel
    IgG subclasses
    CBC w/diff
    Vitamin D, 25-hydroxy
    ASO
  2. Sushi

    Sushi Moderator and Senior Member Albuquerque

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    You would want Vit D 1,25 too, and I'd think inflammatory cytokines would be useful. My doc tests sCD 14, C4a and some other things that I could pass on if you think you could get them

    Best wishes,
    Sushi
  3. SOC

    SOC Moderator and Senior Member

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    USA
    You might also want to consider CD8+ and CD4+ cell numbers. Sometimes ME/CFS immune abnormalities show up there rather than (or in addition to) in NK cell function. I second Sushi's suggestion that you also have your immunologist look at inflammatory cytokines.
  4. August59

    August59 Daughters High School Graduation

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    Upstate SC, USA
    Hey Scavo86 - In your list of test you have the EBV EA (r+d) IgG. What does the "(r+d)" stand for? I know our test in the States are different from Englands, but I have never seen that and was curious. Thanks
  5. Scavo86

    Scavo86 Senior Member

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    England
    HI August...I need to take Immunology 101 myself, but I believe them to stand for Early Antigen diffuse (EA-D), and Early Antigen restricted (EA-R). I think they just give a handle on the the infection and how far down the road with it you are/whether it's persistent reactivation. What might also help is the website which is on the sticky in this particular forum which details what all lab tests means exactly. Probably better than relying on me, would you really want to trust a 26 year a trainee lawyer ;) Hope that helps nonetheless.
  6. IreneF

    IreneF Senior Member

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    Make sure the NKC assay is done by flow cytometry. Results should be in lytic units (LU). I'm not sure how widely available this test is.

    Most of the other tests will show if you've been exposed to any of those organisms. It's not the same as having an active infection. In my case I show exposure to nearly everything, but the numbers (the amount of antibody) vary over time. The result that was the most obviously abnormal for me was the NKC functional assay.
  7. WillowJ

    WillowJ Senior Member

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    I'm hoping to get tested for some of these things, too....
  8. ukxmrv

    ukxmrv Senior Member

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    Hi Scarvo, are you seeing a NHS or private immunologist? Do you know which hospital the will be using the lab of?

    I'm in London and have seen a few myself. If NHS they offer very few useful tests and if private it will vary depending on the lab.

    Good luck!

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