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Scientists discover a pathway that monitors a protein import into mitochondria

AdamS

Senior Member
Messages
339
http://news.mit.edu/2018/countering-mitochondrial-stress-biologist-discover-mitocpr-pathway-0413
A duo of MIT biologists has revealed what happens when a traffic jam of proteins at the surface of the mitochondria prevents proper import. They describe how the mitochondria communicate with the rest of the cell to signal a problem, and how the cell responds to protect the mitochondria. This newly-discovered molecular pathway, called mitoCPR, detects import mishaps and preserves mitochondrial function in the midst of such stress.