I have been taking LDN, and am up to .7 daily. Yesterday I thought I was taking a Motrin, and instead popped a Percoset in my mouth. By the time I realized my mistake, I was feeling deathly ill. I was nauseous and my blood pressure had risen by thirty points. I spent a very bad night with my heart pounding in my ears, unable to sleep deeply and for long. I called the pharmacy but most pharmacists nowadays just read off a computer screen and don't seem to know anything. (The pharmacy where I got the LDN from was closed.) He seemed to think that I had been taking Percoset all along and had decided to take LDN. I explained that I wasn't on painkillers, that I had mistakenly taken just one, but he wasn't much help. He said that I had gone into instant withdrawal symptoms. When I got up this morning, I immersed my feet in Epsom salt water, and my blood pressure dropped to normal. When I took my feet out, it climbed again. I have left a call with my Rheumatologist and am trying not to panic. I wish I knew if this was going to stop soon!