Hunting down the cause of ME/CFS & other challenging disorders - Lipkin in London
In a talk to patients in London on 3rd September, Dr. W. Ian Lipkin described the extraordinary lengths he and his team are prepared to go to in order to track down the source of an illness, with examples ranging from autism to the strange case of Kawasaki disease.
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SAH to SAM-E Conversation enzymes and cofactors?

Discussion in 'General Treatment' started by DREBS, Jan 2, 2014.

  1. DREBS

    DREBS

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    Texas
    I always do my own research before asking a question that I could have gone and looked up myself but I am simply having a hard time finding the key players in converting S-adenosylhomocysteine hydrolase to SAM-E.

    I'm assuming, just by looking at the cycle and what the numbers saying either something is draining my Sam-e (creatine demand or methyl doners) or it's not properly getting converted to SAH. So my question is around the area of what it needed to convert SAM-E to SAH.

    I've read Phosphatidyl-ethanolamine, PMT (
    phenol O-methyltransferase) and many moreā€¦ I don't know how accurate these are and how you would go about supporting them?

    My Methionine is elevated/ borderline high in amino acid plasma
    My SAM-E is lower 223 REF RANGE 221-256
    However my SAH is high 56.4 REF RANGE 38-49
    As well as my Adenosine 26.9 REF RANGE 16.8-21.4

    Active folate 361 REF RANGE 400-1500
    Oxidized Glutathione barley out of range HIGH
    Reduced glutathione barley out of range LOW

    Per methylation pathway test

    Thanks for you time!
     
    Last edited: Jan 2, 2014

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