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RTX causing NK cell lymphocytosis

Discussion in 'Rituximab: News and Research' started by Sherlock, Aug 29, 2012.

  1. Sherlock

    Sherlock tart cherry etc. for joints, insomnia

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    Czechosherlockia, USA
    Bikechick Kati's blood tests:
    http://bikechick06.blogspot.com/2012/06/week-11-wrap-up.html

    As her serum B cells went to zero from the RTX, her NKs went from 140 to 413.

    Are there similar reports, either directly from patients or in published papers? I hadn't heard of such a thing when RTX is used in hematological malignancies.
     
  2. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    australia (brisbane)
    interesting, do u know if the nk function improves not just numbers??
     
  3. Sherlock

    Sherlock tart cherry etc. for joints, insomnia

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    Czechosherlockia, USA
    Hi, heapsreal. As tl activity, all I have at this point is the indirect evidence of Jacque's recent account on how a longstanding infection was wiped out after taking the RTX (as part of Kogelnik's pilot study).

    I agree with you that it's very interesting. It's a whole other angle besides quelling autoimmuntiy or excessive inflammatory cytokines.
     
  4. lansbergen

    lansbergen Senior Member

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    This is encouraging but the lymphocytosis should not stay too long.
     

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