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Rs6323 - MAO-A - What this gene does if its bust

Discussion in 'Genetic Testing and SNPs' started by snowathlete, Mar 27, 2012.

  1. musicchick581

    musicchick581 Senior Member

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    I think I tried GABA a few years ago before I knew about this stuff and it gave me more panic attacks. I could be wrong though...I'm going to take an AAE and OAT urine test so it should test that. Hopefully they are accurate.
     
  2. Gondwanaland

    Gondwanaland Senior Member

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    How about LDN for this case? Does anyone have experience with it?
     
  3. pemone

    pemone Senior Member

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    Apparently having the T allele for MAO-A RS6323 means you do not convert catecholamines like epinephrine / adrenalin to metanephrines efficiently. Men have only one half of the allele pair; women have both sides. Does anyone know of a study that quantifies this effect? Specifically what percentage of this conversion gets impaired for people with the T allele?

    I'm trying to understand if this is a moderate 5% downregulation, or if it is a very serious 60% downregulation.

    I would also like to know what other SNPs would downregulate this same conversion.

    I have a problem with high adrenalin and my metanephrines stay always in normal range. So my biochemistry appears to exactly match what these genetics suggest might happen.
     
    WoolPippi and Gondwanaland like this.

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