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Rs6323 - MAO-A - What this gene does if its bust

Discussion in 'Genetic Testing and SNPs' started by snowathlete, Mar 27, 2012.

  1. musicchick581

    musicchick581 Senior Member

    I think I tried GABA a few years ago before I knew about this stuff and it gave me more panic attacks. I could be wrong though...I'm going to take an AAE and OAT urine test so it should test that. Hopefully they are accurate.
  2. Gondwanaland

    Gondwanaland Senior Member

    How about LDN for this case? Does anyone have experience with it?
  3. pemone

    pemone Senior Member

    Apparently having the T allele for MAO-A RS6323 means you do not convert catecholamines like epinephrine / adrenalin to metanephrines efficiently. Men have only one half of the allele pair; women have both sides. Does anyone know of a study that quantifies this effect? Specifically what percentage of this conversion gets impaired for people with the T allele?

    I'm trying to understand if this is a moderate 5% downregulation, or if it is a very serious 60% downregulation.

    I would also like to know what other SNPs would downregulate this same conversion.

    I have a problem with high adrenalin and my metanephrines stay always in normal range. So my biochemistry appears to exactly match what these genetics suggest might happen.
    WoolPippi and Gondwanaland like this.

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