I tried to post this on Harman's comments:
Dear Isabel,
I am afraid even you have got it wrong. I am a retired professor of medicine at UCL and have a lot of experience with designing therapeutic trials. The PACE trial is completely valueless because it breaks the most basic rule of reliable trial design - it is unblinded and has subjective end points. Ask any trials designer and they will tell you this is a waste of time. The fact that Oxford University is involved means nothing - there are people who do not understand what they are doing in all major universities.
The reason the patients are vociferous is that they are being forced to accept very poor science. If I Had ME and realised just how bad this trial is I would be spitting blood as well. This is the Emperor with No Clothes in Spades. Just sit next to a professor of clinical pharmacology at dinner sometime and ask about this trial - it is about time the psychiatry profession realised they can no longer get away with this sort of rubbish.
But I don't think I am logged in. I cannot cope with all these logging in procedures. If anyone like
@Dolphin can post it by proxy then that would be good. Sorry for being a wimp.