Hi All, I've been working on this document for awhile, as these are common questions and situations which come up over and over. I've identified 17 roadblocks to successful methylation and how to get around them. I think I've run into most of them - lol. Hopefully others can benefit from my experience and the collective experiences of others. I have it geared towards ME/CFS patients - being super cautious so you don't make yourself worse - but anyone trying methylation treatment for whatever reasons should find it useful. 3-27-16 - I have revised the section on metal chelation. Basically, the only type of chelation I suggest is Cutler frequent dose chelation. Also updated the link to find a methylation practitioner. 7-22-2014 - I have added a new section regarding Lithium Deficiency and a few other minor changes. 7-28-2014 - I have added a new section regarding Rich Vank's Simplified Methylation Protocol and the discontinuation of the General Neurological Health Formula.