Hello, Had some more questions on rituximab--appreciate any assistance. Also please feel free to point out earlier posts if these issues have already been addressed. 1. Why the infusion on day 14? Does the initial infusion miss some of the B cells? 2. The follow on infusion on Month 3, 6, 9. etc. These are to keep depleting the B cells? Can this eventually be spaced out to once per year or twice per year? 3. What happens to the good antibodies that we have after B cell depletion ..i.e. antibodies to vaccines etc.? 4. There are several case reports of colitis following RTX therapy. Has this occurred in any CFS patients? Thoughts? http://www.gastroenterologyandhepat...ulminant-colitis-following-rituximab-therapy/ Thank you.