I hope you'll weigh in there Eric. Combined with the fact, already mentioned here, that symptoms during and after infusion was pretty much similar in both groups, and that "All patients were given oral cetirizine 10 mg, paracetamol 1 g, and dexamethasone 8 mg prior to infusion." really indicates patients had no idea. The fact that all patients where given such a cortisol dose would really indicate that the placebo patients could just as easily have felt "something" during the infusion. The Rituximab doesn't do anything until long after the infusion anyway (even in RA and other syndromes), unless there's an infusion related emergency (of which there wasn't in the study).