I am not sure if anyone knows this yet, but I know many of us have problems developing allergies to pretty much anything. Has anyone heard if RTX has helped mast cell problems within the clinical trials? This is one of my worst symptoms. I'd be fine if only this part would go away. Well some days I feel that way anyways... Feel free to tag someone too if you think they may know or have a better understanding of RTX in relation to mast cells in our disease.