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Ridge on toenails

Discussion in 'Skeleton, Skin, Muscles, Hair, Teeth, and Nails' started by Jenny, Feb 18, 2010.

  1. Jenny

    Jenny Senior Member

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    After a period of severe relapse, I get a horizontal ridge or raised band on both big toenails. The length of it corresponds to the length of time in severe relapse.

    I wondered if this could provide a clue to what's going on in the body but an internet search gives lots of contradictory diagnoses and vague stuff about toxins.

    Anyone else have this, and anyone have any idea what it could mean?

    Jenny
  2. gracenote

    gracenote All shall be well . . .

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    I notice that kind of ridge - more like a horizontal (speed) bump - on my right thumbnail. I've wondered, too, as it does seem to correspond to changes in my body or medication protocols.
  3. wciarci

    wciarci Wenderella

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    I recall that this is due to a B12 or folate deficiency? I think

    Wendy
  4. Jenny

    Jenny Senior Member

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    Thanks Wendy

    I've been doing Simplified Yasko for 2 years....

    Jenny
  5. wciarci

    wciarci Wenderella

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    Oops. That was my only guess. I have been treating for methylation block for years and have both horizontal ridges and vertical lines.

    Wendy
  6. Sunday

    Sunday Senior Member

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    Even so, it still might be possible that you have the deficiency. If you're taking the B12 in the form of cyanocobalamin, many of us can't convert that into the active B12s we can actually use and absorb; it's a very inactive form but the most common one used. If you're taking B12 in the form of hydroxycobalamin, that's a bit more active, but still has to be converted into a usable form by the body - and many of us can't do that. In the case of folic acid, that's another form that needs to be converted and may not be; methylfolate is the active form.

    Because we have more trouble than the general population converting inactive forms of vitamins, if you are treating for methylation using these forms, you may still not be getting enough B12. In fact, taking inactive vitamin forms sometimes blocks the receptors for the active forms, so you get nothing at all. High blood (serum) counts of B12 tend to indicate not that you have a lot of B12 in your system, but that it's swimming around in your bloodstream because it's not landing on the receptors properly. The only way people with neuro problems can accurately measure B12 levels is in the cerebral spinal fluid.

    This is sort of the babyspeak version of some of the stuff I have learned on the "Hidden Story" B12 protocol thread. There's a lot to be learned about methylation and B12 deficiencies. Some think this protocol is too drastic, but while I don't enjoy startup symptoms, I can really really feel the progress after 4 months. I'm wondering if this years-long methylation treatment is having noticeable effects for you?
  7. Carrigon

    Carrigon Senior Member

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    I haven't seen it on my toenails, but I have seen it on my fingernails. I get ridges and pits in the nails. I've always thought it had something to do with the disease.
  8. Jenny

    Jenny Senior Member

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    Thanks Sunday - no the methylation protocol hasn't helped me I'm afraid. I'm still doing a version of it - I was doing Rich's protocol until 3 or 4 months ago, but now I've substituted methylB12 (5000mcg) and active B12 dibencozide (3000mcg). I still take Folapro and sam-e.

    I've read the 'Hidden Story' posts - ramping up in the way suggested would be just too difficult for me at the moment. Because my symptoms fluctuate so much anyway and I'm doing lots of other things as well it would be impossible to identify any positive or negative responses to the doses. I certainly don't feel any immediate effect from any of the different B12s or the folates, and never had any probs starting them as some people do. Not sure what that means though!

    I do have some of the SNPs that affect methylation though so I think I do need to do something in this area.

    Jenny
  9. Athene

    Athene Never give up

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    I've had these ridges in my nails and they correspond with ME relapses. When I had my heart operation the doctor told me people sometimes get them after their heart has been through a trauma, eg heart attack or surgery. He said I would get them after my heart op and sure enough I did. So I think they can be caused by various things.
  10. Sunday

    Sunday Senior Member

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    I'd never heard about the heart connection, that's interesting. One thing about this DD is, I'm learning a lot!
  11. wciarci

    wciarci Wenderella

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    Wow, am I learning a lot from posts. I am changing many of my supplements. Thank you Sunday. Thank you Jenny for posting this thread, I hope you feel better, I know how it feels.

    wendy
  12. Martlet

    Martlet Senior Member

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    Carrigon

    Do you by any chance have psoriasis? I ask because of the pitting.
  13. Scarlett

    Scarlett

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    I have horizontal ridges on both thumb nails and vertical ones on my fingernails. I have been ill for about two years, and have been on cyano injections every month for a lot of that time because of low B12 levels - I stopped the injections just before Christmas because I wasn't convinced I was getting any benefit from them... around the time I was entering into a bad relapse. The ridges on my thumbs I think probably line up with the start of the relapse - interesting that they might have a connection with B12, maybe I should get a new blood test done and see how my levels are doing.
  14. Athene

    Athene Never give up

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    http://www.normanallan.com/Med/askdr/horizontal.htm

    I found this web page with photos of different types of nail ridges and different causes. It mentions heavy metals poisoning, liver problems, and metabolic diseases amongst other things. Quite interesting.
  15. Jenny

    Jenny Senior Member

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    Thanks Athene

    It says my ridges are a marker of past severe illness - well I kind of knew that!

    Interesting explanations of other nail problems - though I do always wonder what their evidence is.

    Jenny
  16. Adam

    Adam *****

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    Exactly the same for me. And now I have black line (sometimes fade to grey and then back to black again) Vertically on thumb nail!
  17. SaraM

    SaraM Senior Member

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    Vertical lines on all of my nails . The moon parts of the nails have also disappeared.
  18. Jenny

    Jenny Senior Member

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    Hi SaraM

    Half moons are interesting - the only ones I have left are on my thumbs. People on the CPn (chlamydia pneumonia) board have talked about this - some say that half moons returned after treatment with combinations of abx.

    Jenny
  19. SaraM

    SaraM Senior Member

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    Hi Jenny,

    Thanks for the info.I was recently tested for Chlamydia pneumonia and the result came back negative although I had got pneumonia years ago. I also took ABX for one week just a few days ago, but could not continue due to side effects and noticing no improvement.
  20. Scarlett

    Scarlett

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    For about a year they thought I might have Pernicious Anaemia, so I joined the Pernicious Anaemia Society in the UK - they have a great forum. Interestingly, most of the members mention a lack of moons on their nails - quite possibly caused by a deficiency in B12 / folate / ferritin. I have large moons on all my nails, but I am on B12 injections monthly.

    Thanks for the link to the nail info, looks interesting

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