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RiboGen for ME/CFS

Discussion in 'Alternative Therapies' started by Lou, Oct 31, 2014.

  1. Lou

    Lou Senior Member

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    This is a new product offered by Life Extension that I haven't tried but appears somewhat promising. Wondered if anyone here had heard of it or used it?

    According to the article a molecule named roburin derived from French oak trees improve functioning of our cellular ribosomes.

    The human studies done on an extract of roburin, Robuvit, were not described in much detail, but listed the following reductions of symptoms after use of 200 mg/day for six months:

    18% reduction in weakness and exhaustion

    44% reduction of un-refreshing sleep

    29% reduction in short term memory impairment

    63% reduction in muscle pain

    51% reduction in headaches

    47% reduction in tender lymph nodes

    Additionally, there were substantial reductions in sensitivities to noise, foods, meds, and chemicals. Also, reductions in dizziness, depression, mood swings and allergies were noted.

    Almost sounds to good to be true. After recently throwing two near full cabinets of useless supplements away I've sworn off trying new products for now. If someone tries this please report your results.
     
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  2. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    I use several Life Extension products and would be open to trying another. Here's a study using it for CFS:

    Improved management of primary chronic fatigue syndrome with the supplement French oak wood extract (Robuvit®): a pilot, registry evaluation.
    http://www.ncbi.nlm.nih.gov/pubmed/24231834

     
  3. Gingergrrl

    Gingergrrl Senior Member

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    Is this in any way related to Riboceine or a totally different product? I have never tried either of them but just curious!
     
  4. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    Riboceine is not related to Ribogen.
     
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  5. invisiblejungle

    invisiblejungle Senior Member

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    I read about this is the most recent issue of the Life Extension Foundation magazine. This study was actually done a year ago, so I'm surprised that we haven't heard any other testimonials about this supplement.
     
  6. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    I ordered three bottles (90-day supply) of RiboGen from this website:
    https://www.drvitaminsolutions.com/...rench-Oak-Wood-Extract-30-Vegetarian-Capsules

    I decided to go with them because I could get 10% off my order with their coupon, and when I signed up for an account, then signed up for their newsletter, I received a $5 off coupon, bringing my bottle price down to $22.70 each when I bought three bottles.

    This Life Extension product was added to the Life Extension product line on October 1, 2014, and it hasn't made it into many online suppliers yet.
    http://www.lef.org/Vitamins-Supplements/item01900/RiboGen-French-Oak-Wood-Extract
    Life Extension will have an Annual Sale beginning around November 15th with lowest prices of the year.

    You can get it on Amazon from a few suppliers:
    http://www.amazon.com/gp/product/B00OZV8SZY
    It's going for $26.48/bottle there (product & shipping).

    Here are two more studies that were done on healthy volunteers:

    Effect of the French oak wood extract robuvit on markers of oxidative stress and activity of antioxidant enzymes in healthy volunteers: a pilot study.
    http://www.ncbi.nlm.nih.gov/pubmed/25254080


    Absorption, metabolism, and effects at transcriptome level of a standardized French oak wood extract, robuvit, in healthy volunteers: pilot study.
    http://www.ncbi.nlm.nih.gov/pubmed/24354337
     
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  7. shannah

    shannah Senior Member

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  8. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    I'm NOT surprised we haven't heard more about this. Distribution takes time.

    There's only been one study done on CFS patients, published in print Panminerva Med. 2014 Mar, published online 2013 Nov 14 (?). http://www.ncbi.nlm.nih.gov/pubmed/24231834

    The only distributor of the patented extract Robuvit®, is Life Extension, who made it available October 1, 2014, under the product name Ribogen.
    http://www.lef.org/Vitamins-Supplements/item01900/RiboGen-French-Oak-Wood-Extract

    BTW, the Prohealth article is a reprint from a Life Extension article, which only became available online within the last two days.
    http://www.lef.org/Magazine/2014/12/New-Option-For-Chronic-Fatigue-Syndrome/Page-01

    I ordered Ribogen (see post #6) and started taking it on November 10th. No complaints so far, but it's too early to tell if it's working or not. I'll definitely be posting my progress in this thread.
     
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  9. shannah

    shannah Senior Member

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    I'll be watching with interest CFS...
     
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  10. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    I've been taking Ribogen for seven days now and there are a few subtle things happening:

    1. Change in the types of food I want to eat. I wouldn't say I'm hungrier or that I have hypoglycemia. I get the hunger that says, an apple or a candy bar won't do, I need a real meal. I remember a 8 months' pregnant woman saying to me one time, "a bag of chips won't do, I need a sandwich." That's what I've been experiencing. Fortunately, I have Meals on Wheels delivery, and they deliver 14 nutritionally balanced meals every week, similar to TV dinners that you can pop in the microwave. Without those, I don't know what I would do.

    2. Slight change in how my body feels. I just started to notice today when I woke up that I had slightly less pain in my arms, especially my forearms. I don't know what it is about the forearms, but they ached like crazy when I first had CFS/ME. I also have FM.

    No change in energy or overall pain levels yet.

    I don't want to post about things that I think are changing too soon, as I don't want to give false hope, but I also don't want to hold information back, because I know some of you might be thinking about trying Ribogen and want to hear something positive first.

    ProHealth now stocks Ribogen, if you want to compare prices.

    My history: I'm 60 years old, came down with CFS/ME at age 36 with an acute viral onset. My activity level is a 3, which means I can putter around on the computer a few hours a day, but not much else. My trash is piling up because I'm too weak to take it out. About six months ago I gave up walking outside even a few minutes a day, just because it takes a lot out of me. I don't get dressed into street clothes - I wear a nightgown all day (Wow, does this cut down on the laundry!) I need at least 9 hours of sleep in order to feel my best, which isn't that great.

    When I'm not on the Internet, I'm watch TV or reading books a few pages at a time. Before I came down with CFS I worked a full-time job, could cycle 15 miles and work out in a gym after work. I used to be a competitive swimmer.
     
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  11. Gingergrrl

    Gingergrrl Senior Member

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    @CFS_for_19_years thank you for the detailed report on Ribogen and for sharing more of your story. I enjoy learning more about people here and consider all you guys my extended family! I am so glad you have Meals on Wheels and that is a great support. Is there a neighbor or anyone who can help you with the trash?
     
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  12. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    I found another article on Ribogen, published online November 14, 2014, written by the same authors as the first article here:
    http://www.ncbi.nlm.nih.gov/pubmed/24231834
    -- -- - - - -- -- - - - - - - - - - -- - - - -- - - - - -- - - - - -- - - - - - - -- - - -
    QR (Quercus Robur Extract, Robuvit) supplementation in subjects with chronic fatigue syndrome (CFS) and increased oxidative stress. A pilot registry.

    http://www.ncbi.nlm.nih.gov/pubmed/25394351
    MAF stands for Multidimensional Assessment of Fatigue
    http://www.rheumatology.org/Practic...Multidimensional_Assessment_of_Fatigue_(MAF)/
     
  13. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    I did a PubMed search on the words "quercus robur," the Latin name for French oakwood extract to see if there were any explanations about how it worked.

    Influence of oak wood polyphenols on cysteine, homocysteine and glutathione total levels and PON1 activities in human adult volunteers - a pilot study.
    http://www.ncbi.nlm.nih.gov/pubmed/25367762
    Gen Physiol Biophys. 2014 Nov 4
     
    Last edited: Nov 17, 2014
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  14. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    I emailed Life Extension yesterday to ask about how their supply of Ribogen would hold up if a million or so patients decided to use it. I also asked about the directions on the bottle that say to no exceed the recommended dose of 200mg/day.

    Here's their reply:
     
  15. Little Bluestem

    Little Bluestem Senescent on the Illinois Prairie ❀❤✿Ƹ̵̡Ӝ̵̨̄Ʒ✿❤❀

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    This sound like it was people with non-ME CFS.
     
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  16. Lou

    Lou Senior Member

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    Sure does, I'm going to wait and see how it goes with cfs___for 19years.
     
  17. Kiwi Jack

    Kiwi Jack

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    I purchased some today. Will give it a shot ....
     
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  18. Unduki

    Unduki

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    Hi, re-new here. I left all such groups years ago because I felt the answer wasn't in the synthetic drugs. I've been doing pretty good. There was a deep need within me to get back to the earth and all she offers. I think it was a good choice.

    I received an email from Pro Health about this French Oak Wood Extract. I read the really long article and just know in my bones this is going to do some good. I immediately ordered my 90-day supply of RiboGen. It's backordered, actually, but only until Dec. 11, so I can deal with that.

    Thanks for posting about this, cfs for 19 yrs. I'm looking forward to your progress reports. I'll post some of my own.
     
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  19. Gingergrrl

    Gingergrrl Senior Member

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    @Unduki I got that e-mail from Prohealth too and immediately thought of @CFS_for_19_years and wondered how she was doing on Ribogen. I have recently started some new supplements so not ready for Ribogen yet but it is intriguing. Please keep us posted how you do on it once you try it.
     
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  20. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    I have no big changes to report yet. As soon as I finish my first bottle, I'm going to take it twice a day as opposed to the stated once a day directions and see if there's any change.

    This was received as an email reply from Life Extension:
    ProHealth isn't the only place that stocks it. In addition to getting it directly from Life Extension and Amazon, check out other places here:

    http://www.thefind.com/search?query=ribogen -aor -atp

    There's another product by the same name, manufactured by AOR, that has nothing to do with the product Ribogen that uses the proprietary ingredient Robuvit.
     
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