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Resveratrol appears to restore blood-brain barrier integrity in Alzheimer's disease

ScottTriGuy

Stop the harm. Start the research and treatment.
Messages
1,402
Location
Toronto, Canada
https://www.sciencedaily.com/releases/2016/07/160727140041.htm

Resveratrol, given to Alzheimer's patients, appears to restore the integrity of the blood-brain barrier, reducing the ability of harmful immune molecules secreted by immune cells to infiltrate from the body into brain tissues, say researchers. The reduction in neuronal inflammation slowed the cognitive decline of patients, compared to a matching group of placebo-treated patients with the disorder.

...

Previous studies with animals found that age-related diseases--including Alzheimer's -- can be prevented or delayed by long-term caloric restriction (consuming two-thirds the normal caloric intake). The researchers studied resveratrol because it mimics the effects of caloric restriction by also activating proteins called sirtuins.

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These new findings support the notion that resveratrol decreases swelling that results from inflammation in Alzheimer's brain," says Turner. "This seemingly paradoxical effect is also found with many of the drugs that are beneficial for patients with multiple sclerosis -- another brain disease characterized by excessive inflammation."
 

Marky90

Science breeds knowledge, opinion breeds ignorance
Messages
1,253
If we look away from all the preliminary conclusions those researchers draw about the disease, then some of those findings are quite interesting indeed. With regards to alzheimers, I guess the hype will hinge on how they defined "cognitive improvement".
 

shannah

Senior Member
Messages
1,429
Some Lyme protocols use resveratrol.

I tried it for a long period of time and didn't notice any benefit.
 

Daffodil

Senior Member
Messages
5,875
wow interesting

is every single unsolved CNS disease related to blood brain barrier??!
 
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