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Resveratrol appears to restore blood-brain barrier integrity in Alzheimer's disease

Discussion in 'Other Health News and Research' started by ScottTriGuy, Jul 28, 2016.

  1. ScottTriGuy

    ScottTriGuy Stop the harm. Start the research and treatment.

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    Toronto, Canada
    https://www.sciencedaily.com/releases/2016/07/160727140041.htm

    Resveratrol, given to Alzheimer's patients, appears to restore the integrity of the blood-brain barrier, reducing the ability of harmful immune molecules secreted by immune cells to infiltrate from the body into brain tissues, say researchers. The reduction in neuronal inflammation slowed the cognitive decline of patients, compared to a matching group of placebo-treated patients with the disorder.

    ...

    Previous studies with animals found that age-related diseases--including Alzheimer's -- can be prevented or delayed by long-term caloric restriction (consuming two-thirds the normal caloric intake). The researchers studied resveratrol because it mimics the effects of caloric restriction by also activating proteins called sirtuins.

    ,,,

    These new findings support the notion that resveratrol decreases swelling that results from inflammation in Alzheimer's brain," says Turner. "This seemingly paradoxical effect is also found with many of the drugs that are beneficial for patients with multiple sclerosis -- another brain disease characterized by excessive inflammation."
     
    PatJ, Lindberg, Mary and 5 others like this.
  2. Marky90

    Marky90 Science breeds knowledge, opinion breeds ignorance

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    If we look away from all the preliminary conclusions those researchers draw about the disease, then some of those findings are quite interesting indeed. With regards to alzheimers, I guess the hype will hinge on how they defined "cognitive improvement".
     
    Valentijn likes this.
  3. shannah

    shannah Senior Member

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    Some Lyme protocols use resveratrol.

    I tried it for a long period of time and didn't notice any benefit.
     
  4. Daffodil

    Daffodil Senior Member

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    wow interesting

    is every single unsolved CNS disease related to blood brain barrier??!
     
    Last edited: Jul 28, 2016
  5. hixxy

    hixxy Senior Member

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    Has blood brain barrier even been identified as a problem in ME yet?
     

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