Hi Brenda, Do what is working for you. Follow the clues of healing. The lack of all sorts of things can break the system, including b2 and manganese. If and when that runs out of further healing perhpas you will need to look for other things or maybe it will be healed. Not everybody has the same things. There are a fair number of people here that have things going on that most definitely do not fit the b12-folate patterns. There are others with very complex compound patterns and things that if sucessfully treated will simplify the picture aloowing the next stage. I found that it is one layer after another, each one requiring it's own solution. So right now you are working on this layer with sucess. The B2 and manganese solution appears rather rare and/or is rarely recognized. Starting out by declaring your own post as "this is a load of rubbish" seems like a strange header for your post to me. But then, I guess it works for you. As to your lack of low potassium thats great. Some have no problem. Some have problems that haven't caused the type of damage that triggers the high rate use of potassium to heal. The majority of people can take any or all of the various supplements and never need a bit more potassium than they are eating. It happens with a specific set of people with specific sets of symptoms when their healing starts up which can occur with any of the following so far depending on the person; adb12, mb12, Hycbl, cyanocbl (rare according to literature), methylfolate, folic acid, folinic acid, vitamins A, D, C, b-complex, E, magnesium, zinc, SAM-e, TMG, L-carnitne (fumarate or acetyl) any of a number of amino acids, and probably just about any essential mineral, supplement or vitamin. The genetic variations on all these things is huge. I want to build a database that captures and indentifies ALL these variations including the b2-manganese one. Often the challange is finding that first area of response from which to get the clues of healing to then follow up on. It's like some of those puzzles, first you have to find the piece that unlocks it. So have fun and good health.