I intend to post my experiences here as they come. I have been sick for almost a decade, not being able to work, study or socialize. My symptoms are primarily these: Brain fog, memory problems, concentration problems, low blood pressure and high heart rate when standing up, numbness borderlining not being able to feel at all, I can't feel the position of my limbs, severe insomnia, barely being able to feel any emotion, and much more which makes it unbearable to live. What I hope to achieve from doing the methylation protocol is mainly better sleep (in the long haul), being able to feel emotions more (another PWME had that symptom improve with SAM-e ++), less concentration problems and not getting dizzy when standing up. Hopefully I'll get a lot better all throughout, but the core of what hope will improve is that. I have bought the supplements for a methylation protocol from Holistic Heal. In case anyone who's new to this wonders how they look, I uploaded an image here (see below). I'll follow Richvank's methylation protocol. General Vitamin Neurological Health Formula, beginning with a tablet and increasing the dosage as tolerated to 2 tablets daily. Hydroxy B12 Mega Drops, 2 drops under the tongue daily (not sure if I am able to hold them there long enough for it to work) MethylMate B: 3 drops under the tongue daily Folinic acid: capsule daily (I'll divide the capsules into two, and take half of each of those each day). Lecithin, one softgel capsule daily I will probably begin later this week. First with the multivitamin, than with the other supplements added one by one. I have been on SAM-e earlier, just for some days, and I got the strangest reaction; although I am not able to feel emotions, I got some sort of a feeling blue emotion, although very watered out. If I stuck with it, I might have got the same improvement in being able to feel emotions at all as the blogger mentioned in the link above.