Researchers Use Asthma Drug to Reverse Brain Inflammation and Tau

[Jackb23]

"Inflammation was completely gone from tau mice treated with the drug," Dr. Praticò said. "The therapy shut down inflammatory processes in the brain, allowing the tau damage to be reversed."

The study is especially exciting because zileuton is already approved by the Food and Drug Administration for the treatment of asthma. "Leukotrienes are in the lungs and the brain, but we now know that in addition to their functional role in asthma, they also have a functional role in dementia," Dr. Praticò explained.

"This is an old drug for a new disease," he added. "The research could soon be translated to the clinic, to human patients with Alzheimer's disease."

https://www.sciencedaily.com/releases/2018/06/180608101905.htm


-Would be interesting to see if this helped with brain fog. Has anyone on here ever tried Zileuton? This is a relatively easy drug to obtain. I’m going to add it to my list of things to try.

 

[hixxy]

No, but I've tried monteleukast which is a leukotriene receptor antagonist and it didn't do anything helpful.

 

[Eian Mcneely]

Watchful for the outcome it can bring, no experience with zileuton

 

[Thinktank]

I use boswellia serrata, a leukotriene inhibitor and i find it very helpful for my asthma and for its overall anti-inflammatory effect. It also helps my cognition somewhat.