Hi I had bad effects from Mb12 and Mfolate - huge increase of histamine. I started to titrate Hydroxb12 and folinic acid instead. up to 400mcg Hydroxb12 and 200mg folinic but could only tolerate folinic twice a week. I am also on vit c. b2, magnesium, digestive enzymes, and have been taking Ribose but had to stop. Today I have sores in my mouth which are causing discomfort. Would appreciate advice on what I am short of. Is it folate?