How do I know the difference between a relapse and something else? I've been ill with ME for a year and have been feeling really ill recently the symptoms are a lot worse and the pain is slightly different since when I was first ill. The tiredness is a lot worse and seems to come in waves. i am going to the gp on Monday but to be honest I know he can't do anything except send me for a blood test. So I've been quite reluctant because if it is a relapse the results will come back as normal anyway. I'm 16 btw.