The real issue with enteroviruses is us is there is probably little or no replication. Blocking replication may not have a big effect. The two tissue infection life cycles for enteroviruses so far identified involve minimal replication. There may be some, but its the presence of the virus itself that is likely to be problematic. On the other hand if these substances block viral protein synthesis, then stopping our cells from pumping out viral proteins (an hypothetical issue) could be a good thing.