Home care is the theme for Severe ME Day on August 8th
Why should home care be the theme on Understanding and Remembrance Day for Severe ME on August 8? Helen Brownlie of the 25% ME Group has written an explanation for Phoenix Rising ...
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Refractory Lyme Arthritis May Be Autoimmune

Discussion in 'Lyme Disease and Co-Infections' started by Omar88, Jan 6, 2013.

  1. Omar88

    Omar88 Senior Member

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    http://www.medpagetoday.com/Rheumat...mail=kthrnstephens079@gmail.com&mu_id=5225386

    Activated T- and B-cell responses to an autoantigen in synovial tissue may explain the development of resistant arthritis among a small number of patients with Lyme disease, researchers suggested.
    Robust T-cell responses to an antigen known as endothelial cell growth factor (ECGF) were seen in 38% of peripheral blood mononuclear cells from patients with Lyme arthritis that had not cleared with antibiotic therapy, according to Allen C. Steere, MD, of Harvard Medical School, and colleagues.
    In addition, B-cell-produced antibodies to ECGF were observed in 17% of patients with antibiotic refractory Lyme arthritis, but in no healthy controls (P<0.0001), the researchers reported in the January issue of Arthritis & Rheumatism.
     
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