Discussion in 'Latest ME/CFS Research' started by A.B., Jan 7, 2014.
This study is rather old, but still relevant.
My magnesium tested on the very low end of normal in red blood cells, and high in serum. If I don't take magnesium, I get muscle twitches and loss of gut motility.
Though once I started Yohimbe, I haven't really needed to supplement magnesium. I used to need magnesium twice per day, and now I just need it once on alternating days, at most. Not sure how Yohmibe is doing that, but I'm not complaining
Never got mine in the end, specialist gave me the blood forms but when I got home, local doctors refused arrange to have it done.
That's really frustrating! Can you return to the specialist's surgery for them to order the tests on your behalf?
Same with me: my red cell magnesium is deficient but blood levels are high.
This paper is on sci-hub is anyone wants to read it. Seems like they did a good job of blinding and controlling for expectation and influence and the results look quite strong. Only weakness I see are that it was quite a small sample (15 in treatment and 17 controls) and only lasted 6 weeks so it's unknown if the effect could be maintained. Also the Nottingham Health Profile looks like a bit of a blunt instrument for example going from borderline yes to borderline no on 'tired all the time' would result in a 39% swing in the score.
I've been supplementing magnesium (both topical and oral) for quite a few years.
Serum and RBC magnesium are at the top of the range and have been whenever measured over the years.
I find the supplements very helpful for muscle pain and twitching, sleep and generally feeling calmer, but having high RBC magnesium has done nothing for my ME/CFS. This is gradually getting worse.
Hmm, this is interesting. I didn't know one could have good serum magnesium levels but and low RBC levels. I wonder if that's why oral magnesium never seems to do anything for me. I have most of the problems associated with magnesium deficiency but oral magnesium never helps.
@alicec does the topical somehow get into the RBC's?
Not particularly but you might get better absorption into the blood using the topical route. This in turn might drive more uptake into cells.
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