I'm doing @Freddd 's protocol. I've been on it for 5 months, have the deadlock quartet in place, and I'm titrated up to 6mg Mb12 and 2.5 Adb12. Currently taking 12 mg methyfolate to keep out of insufficiency, as well as about 1,200mg potassium supplemented. Anyway, I'm still feeling pretty non-functional (I'm ME/CFS according to the ICCC, btw) so I'm thinking I should add in SAM-e and r-ribose and see what happens. Would love any advice!! But, especially brands and dosages. Also, any pitfalls with taking them? Also, do you think this is the right move for me, or should I first try to really ratchet up the b12's to a much higher dose? Thank you!!