Discussion in 'Institute of Medicine (IOM) Government Contract' started by Ember, Mar 24, 2014.
By Jennie Spotila
March 24th, 2014
According to Jennie, “ME/CFS patients experience more than fatigue after exertion; we suffer from an exacerbation of all symptoms (including immune symptoms), and 'fatigue' is a completely inadequate word to describe the prostration and collapse.” She writes:
However, the descriptions of post-exertional prostration or collapse vary. The CCC describes the tendency for other associated symptoms within the patient's cluster of symptoms to worsen during Post-Exertional Malaise and/or Fatigue:
But symptom exacerbation, primarily in the neuroimmune regions, defines Post-Exertional Neuroimmune Exhaustion (PENE) according to the ICC:
Such differences matter: “If PEM is equated to fatigue lasting more than 24 hours after exertion – which is reported by Gulf War veterans – the argument that post-exertional malaise is unique to ME/CFS falls apart.”
Actually, the argument might not fall apart even then. What if a large subset of GWI is in fact ME, just ME from particular triggers? If you go back through the epidemics, ME symptoms do seem to vary a bit, cluster by cluster.
However I do think we need PEM/PENE biomarkers to be sure of anything.
I can't relate to the term "PEM," except as a warning sign.
You can also try a Google Site Search
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