I believe I could be suffering from a disease process that is causing me to have high levels of reactive oxygen species or some other oxidative molecules. This could be either systemic or more likely an isolated process in and around the tissues of the nasal mucosa, the eyes, the trigeminal nerves, and even the meninges or other brain tissues. These high levels of oxidative molecules could be the cause for premature vitreous liquefaction with high levels of visual floaters, and more importantly the cause of a chronic pain disorder known as new daily persistent headache, which is an unremitting, bilateral pain in and around the sinus area, related to the ophthalmic and maxillary divisions of the trigeminal nerve. I have been suffering from this headache for over six years without any remission and without a good treatment or explanation. I believe the current treatments and pathologic explanations for this disorder are very lacking and disappointing, most patients don't recover or improve. I would like to know what metabolic or immune dysfunctions you can think of that could be a cause for high levels of ROS being generated in a chronic way, that could be damaging and/or be stimulating nerves to cause them to generate chronic pain signals in that area. I think the answer might be diverse and complex, or simple, but I think there is a good answer and that there are good ways to find out.