I get nerve/neuropathy type pain down my legs alot at night that disrupts sleep but also get nerve pain in my neck and across my shoulders. Generally i use lyrica which has helped but i do want to be less reliant on meds if i can. I have read where people use a fat soluble form of thiamine called benfotiamine and i have recently started this a few days ago at 150mg in the morning to hopefully help with nerve pains etc. In the last few days i have had increased pain with knots around my shoulder blades up into my neck and across my shoulders, mostly on the right side which is where i do get alot of pain and probably some arthritis i guess from work lifting equipment on that side. Im wondering if this stuff increases nerve function if it could be irritating my nerves and causing increased pain. No recent obvious injury etc. I am going to stop it for a few days and see what happens. I am interested to know if anyone else has had a similar issue with vitamin b1 and its other different forms?? cheers!!