A few months ago I had a severe over-methylation reaction b/c I was stupidly taking doses that were way too high. In a short period of time, I had gotten up to 7 mg of MB-12 shot and 2.5 mg of M-folate. It was a disaster with symptoms so bad I thought it might kill me and led my Dr to run a bunch of tests to rule out other causes. I felt today that enough time had passed so I am braving to try again but with MUCH lower doses. For the MB-12 shot, I am only doing 1 mg and for the Folate I am only doing 200 mcg. I realized that my Magnesium supplement (which is a special slow release Magnesium SRT by Jigsaw Health- the only one my stomach can tolerate) actually contains 200 mcg of M-Folate which I never knew! So back when I was taking the Folate, I was actually taking even more than I'd realized due to what was unknowingly in the Magnesium!!! So for now, all I am doing is taking the Folate in the Mag and not adding the extra Folate which I bought. I had planned to take 200 mcg to start so it seemed like what I am getting in the Mag is enough. If I need to increase, I bought a bottle of 800 mcg Folate (which I will cut into quarters.) Does this seem like a good plan? Also, should I do the 1 mg MB-12 shot every day or 3x/wk like I did it before? At the lower dose it seems like every day might be okay? I am tagging a few people just to get confirmation that I am on the right track attempting this again. @Sushi @caledonia and @Valentijn Thank you all so much!