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Quick Question regarding MB12 and Folapro

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by bertiedog, Apr 29, 2013.

  1. xjhuez

    xjhuez Senior Member

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    Yes - nausea, overall ill feeling, and a terrible metallic taste. The one I tried was called Folapro.
  2. Lotus97

    Lotus97 Senior Member

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    I've heard someone else saying they have a problem with supplements in general. They said they take a food b complex. I'm not sure what brand they take, but New Chapter has one. It's kind of expensive and I have no idea if it will work for you.
    http://www.iherb.com/New-Chapter-Organics-Coenzyme-B-Food-Complex-180-Tablets/68
    You could also try coenzymated b vitamins. They're in the active form so you don't have to take as much. I'm also kind of burnt out trying new supplements too. I have unopened bottles of PQQ, Citicoline, and pterostilbene that I bought a few months ago when Swanson was have a big sale.
    I've been taking betaine HCL as a digestive enzyme for the past year or two. I honestly can't tell whether digestive enzymes (of any type) are helping or not. Actually, I can't tell whether most of my supplements are working or not. I've thought about dropping a lot of them, but I've afraid I'll have a crash if I do. I cut back on betaine HCL and TMG recently to see if they were causing symptoms. It's too early to tell, but so far I'm not sure I noticed a difference.
    I don't know if there is a non-methyl donor that stimulates the BHMT. If you think your problem is overmethylation then as I said before you could try B3 and/or hydroxocobalamin, but if you're not taking methylfolate then I'm not sure. Maybe if you're taking a high dose of methylcobalamin along with other methyl donors that could cause problems. Some foods are high in TMG and choline so you could check if you're already getting a lot from your food. If you're COMT -/- then it seems like if norepinephrine is your problem, it wouldn't be from converting too much to dopamine to norepinephrine. I don't know a lot about SNPs so maybe there are other factors involved or maybe COMT -/- isn't a 100% accurate indicator of overmethylation tendency and/or having higher dopamine/norepinphephrine levels. This is what dbkita said recently about that
  3. xjhuez

    xjhuez Senior Member

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    I tend to overreact one way or another to pretty much everything I take. Whether it's leaky brain, leaky gut, both or something else I couldn't say.

    Based on my behavior I suspect low dopamine (and possibly all my catecholamines), however considering there is both tonic and phasic activity, there are several dopamine receptors, it affects areas of the brain differently, etc.. being "low" is vague and pretty meaningless.
  4. Lotus97

    Lotus97 Senior Member

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    Caledonia said she was able to tolerate higher doses after she had worked on her CBS issues. I'm not sure if that's going on with you, but it's another thing to consider. It really is trial and error with these things.

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