Sorry to add yet another LDN thread, but I've been reading them a long time, and I'm still unclear about some things. I'm interested in trying LDN because I have a great deal of back and neck inflammation and a long-standing insomnia problem. People's reactions seem so mixed. For some, it's a big benefit, while others find that all they had were side effects and no benefits. 1. My doctor's office prescribes transdermal LDN. Have any of you found this form to be more beneficial or result in fewer side effects than the other forms? 2. Have any of you still had sleep disturbances at the beginning even if you start with a low dose such as .5 MG first thing in the morning? I think my doctor's office recommends morning doses if you are really sensitive to meds. 3. If you start at a super low dose (@PatJ, I read you started at .125) could you still have side effects? I think it would be hard to have just side effects and no benefits while you are titrating. 4. I know LDN helps some people with brain fog, but have any of you felt more spacey at first? 5. For those who tried LDN, but stopped, what were the side effects you found intolerable? 5. After going on LDN, have any of you discontinued other immune modulators you may have been taking? I take 700 MG of beta glucan a day. This is probably something I'll have to ask about at my doctor's office. 6. If you already take sleep medicine, do you still take it and slowly taper off once you've been on LDN for while? Thanks for taking the time to read all this!