I woke up this morning with slight angiodema/swelling on left side of my face. My face was reddish and hot to the touch but the weird thing is that it was very painful. The pain felt deep, like down to the bones in my face, but was also on the surface of my skin. If I just barely touch my face, it is very painful. It is strictly on the left side and goes from my cheek to under my eye to my temple to above my eye and includes my scalp. I thought it might be mast cell related so I finally took my rescue med, Atarax. This eliminated all swelling, redness, and hot feeling but did not touch the pain. The roof of my mouth and upper gums are also swollen along with my left tonsil and side of throat but this is very common for me with MCAS. The facial pain is completely new and worrisome. Does this sound MCAS related or like nerve pain or something different? I have heard of shingles without the rash (zoster sin herpete) and I have been IgM+ for VZV for several years but don't know if this could match? Do you take Famvir or an anti-viral for nerve pain or am I way off? I did not eat dinner tonight b/c just too risky in case this is MCAS related, I do not want to trigger an anaphylactic reaction from the food. I put this in the neurological forum b/c it really feels like nerve pain, although I am not positive if I know what nerve pain feels like. I put ice on it for hours but it did not help at all and I cannot even have that side of my face touch the pillow, it is too painful. Am hoping it's one of those weird things that just goes away. If anyone has any thoughts, that would be great!