Yes, good point. Since DHEA goes through the liver I myself have from time to time worried and thought about changing my delivery method...so I tried sublibgual which does not go through the liver (got no frinkin idea why. anyone?) but it tastes too awful to take it that way. I never got around to investigating a DHEA cream and I know the dose is different (you absorb differently thru the skin) so it's not a simple switch and would involce recalibrating dose. So far I have not hit on a best way. I just take it by pill so far.