I've been on Equilibrant about 2 months now and have seen some small but noticeable improvements. When I first started it and each time I increased my dose, I felt worse the first day then gradually better over time. I'm only at 1/2 pill per day but hesitant to increase more because its throwing my hormones out of balance. I started a small amount of inosine today and had a pretty significant negative reaction-- extreme sound sensitivity affecting my autonomic nervous system. My question is for those on inosine: is it similar to Equilibrant where it's expected to cause an initial negative reaction followed by a positive reaction? Or is a negative reaction a sign to avoid it? I'll put in a call to Dr. Chia soon but just thought I'd see what others have experienced. Side note: I had an extreme light sensitivity with Valtrex which caused me to discontinue, and some initial mild increased sound/light sensitivity with Equilibrant which went away and actually improved after a while. It seems whatever I'm fighting is messing with brain/sensory nerves.