airway involvement? maybe some only with stomach involvement that may be a indigestion cause instead of inhalation/environmental exposure, some unsure? I know I got ill from exposure in two moldy houses that were very different as was some symptoms and the outcome from each, my airways were heavily involved so no doubt here, now either I got the herpies virus, and EBV virus before and it never caused illness but stayed dormant in the body until these environmental exposures and the severe hypersensitivity disease it caused brought the EBV virus out of hideing and that reaccures everytime a exposure to certain triggers (like mold, chemicals,voc's, allergen, irritants) sets it off or I got it afterwards as a seceptability factor because of the injury from exposure, it doesn't really matter. something I've realized is that yep, when I get a cold or flu or something it does not present like pre-ME/CFS did. and the big notice is that it makes my hypersensitivity reactions more severe again! but also seems to wipe out that bug pretty quick in the process. I don't know about how other ME/CFS'ers view the process in witch their disease accured, but interested in hearing from others. for me this disease is first and formost severe hypersensitivity disease with seceptability to other pathogens, and fungal infection being opportunistic invader just like other pathogens, they all need to be treated. including the hypersensitivity. and I'm pretty possative fibromyalgia is caused by inhalation, sinus/brain involvement so more specificitly are there people with no chronic sinusitis/rhinosinusitis, severe asthma here? environmental exposures can be through inhalation, ingestion, and by durmal /skin, there can be secondary effects to these areas but likely if they are directly involved in your ME/CFS you know it. point is we may all be here because of environmental exposure, in this case the cause needs to be realized as preventive medicine , just like if theres many here that don't get the lengths they need to go to to avoid their triggers, that's important to do with hypersensitivity exspecially when you are reactive to so many things, the immune system is disperate for some relief and it helps the severity overall to practice avoidance of your triggers and it requires paying close attn. to your disease to figure out what a lot of them are and first step is to basicly get all possible triggers out of your living space, food, water, off skin, as much as possible.