I am trying to get my head around the blood tests that I have had recently and whether low globulins are likely to be related to my immune problems? I had a liver test and my globulin was low in that (all other in the test OK). I also had a bone test and that also was fine apart from the low globulin. I also have low platelets and these have been ongoing low for a few years now, but are the lowest they have been for 4 years. My immune system has been really struggling this year, but last year was the best it's been with all my results in range. I have a theory on the cause of this......I take Liothyronine/T3, and last October an Endocrinologist asked me to reduce my dose and since then my immune system has been sliding down, made worse in the past few weeks by also being asked to take Thyroxine/T4 with my T3. I now have a constant sore throat. They are worried that my osteoporosis is being caused by the T3, but if I have to suffer a dodgy immune system instead then I am not much better off.