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Question about 23 & Me-my results are ready, can't find them!

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Misfit Toy, May 29, 2013.

  1. Misfit Toy

    Misfit Toy Senior Member

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    Can anyone help me with what I am about to ask? I went into 23 & Me trying to find if my results are ready....it says "Your results are ready!" Well, where are they? I see genetics, stuff having to do with the family, but nothing like everyone here has where you have letters and minus signs as your signature.

    I never received an email saying anything was ready so I am confused. Does anyone have an idea what or where I should go? And, I can't reach out to 23 & Me. I wouldn't even know what to ask except where are the results with all of the letters, plus and minus signs. I went to the "My Results" part and it talks of "Health Risks," "Drug Response" "Traits," etc.

    Please help me out. I loathe that when you need help, you can't call so many places!

    Spit~
  2. Valentijn

    Valentijn Activity Level: 3

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    http://geneticgenie.org/methylation-analysis/ might be helpful. They show you were to go on 23andme. It's also possible that the raw results don't look like what you've been seeing here ... they're providing results for about 1 million genes, then people feed them into the program on the geneticgenie site to get the methylation and detox charts.
  3. Misfit Toy

    Misfit Toy Senior Member

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    Valentijn, it looks nothing like anyone else's. If I print it out, it will be over 400 pages long. Does that make sense? I don't understand this crap. I am so tired and in pain. I don't get it. It's greek. It's all letters like CC.
  4. Misfit Toy

    Misfit Toy Senior Member

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    rs30101431195859677TT
    rs104947371195862859CC
    rs18690421195864347AG
    rs13768031195866450GT
    rs30085761195869123CC
    rs30101471195871839TT
    rs108014901195872295AG
    rs30085521195881459AA
    rs29239111195883861CC
    rs109219841195891127CT
    rs29238751195892617AG
    rs9840811195901676CT
    rs30101591195903057AG
    rs18690451195904595AA
    rs19014251195908262GG
    rs9855881195908303GT
    rs168391231195908996AA
    rs14519241195909031AA
    rs168391321195909700CT
    rs118040371195912579CC
    rs13768151195912805CT
    rs75173371195914273AA
    rs50245031195915483CC
    rs13768111195915580GT
    rs75378931195915909AC
    rs75169581195916112GG
    rs9845571195916500CT
    rs42958711195916887AA
    rs28782831195919285CT
    rs109219921195927451CC
    rs109219931195927611AA
    rs28782841195928549TT
    rs115805341195930996TT
    rs46580111195932083GG
    rs29239061195932841AA
    rs108014991195934150AG
    rs109219981195934627AG
    rs29239051195935240CT
    rs108015011195935322AG
    rs66832641195936137AA
    rs29239071195938859GT
    rs8965161195939912CT
    rs75150271195940509GG
    rs46578181195941818GG
    rs15977301195945395AC
    rs13768161195950283CT

    This is what it looks like. Does this look right to anyone? I am so confused. o_O
  5. Valentijn

    Valentijn Activity Level: 3

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    That's the raw data. It has to get processed to give you the pretty lists.

    1) Go to https://www.23andme.com/you/download/
    2) Download it to your desktop or somewhere else where you can easily find it again.
    3) Go to http://geneticgenie.org/methylation-analysis/
    4) Hit the "browse" button and find the file that you just downloaded to your desktop (or wherever)
    5) Hit "submit"

    After you get results, if you want to post them here, you can:
    1) Position/scroll the results so that they're nicely displayed on your screen.
    2) Hit the "PrntScr" button on your keyboard.
    3) Open "Paint", which is under "Programs", then "Accessories" on any PC.
    4) Right click on the blank area in Paint and "paste".
    5) Hit the "Select" button in Paint and click and drag to create an outline around the area you want to share (the results).
    6) Click on the little menu icon above the "paste" option in the upper left corner in Paint and select "save as".
    7) Set the location to your desktop or somewhere that you can find it.
    8) Set the "Save as type" to "GIF" or "JPEG", and hit the "save" button.
    9) Create a new post here
    10) Click "upload a file" when your cursor is wherever you want the image to appear in your post
    11) Select "desktop" (upper left side usually) and double click the image of your results
    12) Click the "Full image" option that pops up at the bottom of your post.
  6. Misfit Toy

    Misfit Toy Senior Member

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    http://forums.phoenixrising.me/inde...-the-spitfire.106/view&access_hash=b2d8cf3fa4

    It's in my photo album on here. Last photo.

    Valentijn, the link is above. I have no idea how to put it on here because you can't upload a photo to a thread and I have an apple computer. I wish I understood things more or could figure this stuff out, but I can't. My illness is either that bad, or more importantly, nothing feels that easy. If it hadn't been for you, I would have been in the dark, so thank you.

    Hope some people look at above link of my 23 & Me test. Again...it's beyond Greek to me.

    Thanks!!
    Valentijn likes this.
  7. Valentijn

    Valentijn Activity Level: 3

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    The Spitfire
    I can see it now ... do you want me to put it into this thread to make it easier to discuss them?
    The Spitfire likes this.
  8. Misfit Toy

    Misfit Toy Senior Member

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    Valentijn, that would be great! You really know how to navigate your way around the computer and all of this stuff! Thank you so much..you are a peach!!
  9. Valentijn

    Valentijn Activity Level: 3

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    Here's the result of The Spitfire
    spitfire_methylation.jpg
    The COMT and MAO genes are used to break down dopamine, norepinephrine, and epinephrine. With all of your +/- results, you're probably pretty slow at this. But your VDR results also mean that you aren't producing a lot of dopamine (which turn into norepinephrine and epinephrine), so you might be okay over all. Slower creation + slower break down might mean levels aren't getting too high or too low. But you still might need vitamin D supplementation for the VDR issues.

    MTHFR is used for making methylfolate. You're a bit slow in two, but fine in the one that's the most important of the three. So maybe not a big problem there, but supplementing some methylfolate still might help (or not), and supplementing BH4 might help the A1298C issues. A1298C contributes to BH4 also needed to break down neurotransmitters, so COMT and MAO might not be the only factors slowing that down.

    MTRR is used for producing methylB12. Some problems there, so some supplemental methylB12 might help.

    CBS breaks down homocysteine via the cystathionine pathway. Defects in that gene means that it's happening faster than it should, though your +/+ CBS gene has less of an impact than your other CBS genes. Getting rid of homocysteine isn't a bad thing itself, but being overloaded with the byproducts of that breakdown might be a bad thing. BHMT is an alternative way to use homocysteine, by converting it back into methionine. This seems to be your biggest problem area, with one +/+ and two +/- genes, and can result in low BH4. http://www.heartfixer.com/AMRI-Nutrigenomics.htm#BHMT: Betaine-Homocysteine Methyltransferase recommends phosphatidylserine or phosphatidylcholine for BHMT problems.

    So you might get some benefit from methylfolate and methylB12, since you aren't so hot when it comes dealing with the inactive forms. BH4 also seems indicated, and phosphatidylserine/choline might be good too.
    helen1 likes this.
  10. Misfit Toy

    Misfit Toy Senior Member

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    This is interesting, because I had a test for your neurotransmitters and it came back saying I had super high dopamine. I always do, that and high histamine.

    I don't know what BH4 is. But I do know that phosphatidylserine or choline is something I can't take. I can't take L-serine, but choline...no. I am allergic to soy and also, when I was on it last I ballooned up to being 30 pounds heavier and when I went off of it, I got super sick because I lost 17 pounds in 3 weeks. It was causing me to retain water.

    Also, I just began giving myself B12 shots. Not sure if this is a good idea.

    Thanks, Valentijn!
    Valentijn likes this.
  11. Valentijn

    Valentijn Activity Level: 3

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    Good to know about the high dopamine ... I was very curious about how the COMT/MAO problems were interacting with the VDR/MTHFR problems!

    I have all of the same issues. It's also an area where the interpretation is a bit fuzzy and not well-supported. BH4 can't be supplemented directly, but methylfolate, B3, and vitamin C can help recycle it. It might help get your dopamine down.

    Me neither - let us know how it goes!
  12. Misfit Toy

    Misfit Toy Senior Member

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    Valentijn, I will. I hired Thane from Living Wellness to interpret and give me guidance. Thanks again. Really, I so appreciate it.
    Valentijn likes this.
  13. Bluebell

    Bluebell Senior Member

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    Valentijn likes this.
  14. Bluebell

    Bluebell Senior Member

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    Misfit Toy, how did that go?

    I had not heard of his service before seeing your mention of it.

    I've now found his example video on youtube.
  15. Misfit Toy

    Misfit Toy Senior Member

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    Bluebell, I haven't been able to do the full program and I am not sure I will. There are too many supplements and my system does not like that at all. However, Thane is really nice. I recommend it and he knows his stuff. He also gets back to you if you have a question, pretty quickly. You can like his page on FB and email him.
  16. Bluebell

    Bluebell Senior Member

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    Thank you MT, I will add his service to my big list of methylation links! Can I ask you how much he charges for a video report?
  17. Misfit Toy

    Misfit Toy Senior Member

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    $50. Way less than other people. Some who aren't even doctor's charge too much.
  18. Bluebell

    Bluebell Senior Member

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    Does that fee include only a video, or a written report too?

    Who are the other providers who charge more than $50?

    The only one I know about is Sterling Hill, whose written report is $20, I have heard. (Maybe she does a more expensive report by phone?)

    Is there a website that lists people who do this kind of thing, or how did you hear of Thane?

    I don't know very much about this area, but I'd like to give folks as many options as I can in my thread that lists the options for getting information and help regarding methylation.

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