Review: 'Through the Shadowlands’ describes Julie Rehmeyer's ME/CFS Odyssey
I should note at the outset that this review is based on an audio version of the galleys and the epilogue from the finished work. Julie Rehmeyer sent me the final version as a PDF, but for some reason my text to voice software (Kurzweil) had issues with it. I understand that it is...
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querying raw data in 23andme

Discussion in 'Genetic Testing and SNPs' started by ebethc, Oct 23, 2014.

  1. ebethc

    ebethc Senior Member

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    Can anyone tell me what "VERSION" means in 23andme?

    In the Raw Data section, you can query a gene or SNP... The results show a table with the headers:
    GENE, POSITION, SNP, VERSION, <NAME>'S GENOTYPE

    So, for a particular gene BHLHE41 (with 3 snps) I got these results:

    snp rs4963955, versions C or T, ebethc's genotype TT
    snp rs4963956, versions C or T, ebethc's genotype CC
    snp rs1480037, versions C or T, ebethc's genotype CC

    Is the VERSION listed the bad result(s)? are BOTH C & T bad?
     
  2. Methyl Health

    Methyl Health

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    ebethc likes this.
  3. Valentijn

    Valentijn WE ARE KINA

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    C and T are the alleles (variations). Usually neither version has any impact, or just has a very small impact.

    If you want to know if an allele can cause problems you need to look up the research regarding that SNP. http://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?rs= is the best site I'm aware of. And typically a variation has to result in a missense mutation or a stop-gain (changes in the protein created) to have any real impact.
     
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  4. Strawberry

    Strawberry Senior Member

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    Seattle, WA USA
  5. Strawberry

    Strawberry Senior Member

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    Awesome! Thank you! Is it worth the $40 or so to use the other one?
     
  6. Strawberry

    Strawberry Senior Member

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    Yes, it was $20. :) I will post my results when I figure out how!
     

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